Protein Purification
MilliporeSigma™ Calbiochem™ Porcn Inhibitor IV, LGK974
A cell-permeable inhibitor of Wnt secretion from L-cell Wnt1/2/3/3a/6/7a/9a transfectants (IC50 from 50 pM to 1.1 nM).
MilliporeSigma™ Calbiochem™ APT1 Inhibitor II, Cpd21
A cell permeable acetylpiperazine derivative compound that acts as a selective and reversible inhibitor of lysophospholipase 1 (LYPLA1; IC50 = 840 nM, Ki = 300nM) without affecting the activity of LYPLA2 and 25 other serine hydrolases in mouse BW5147 T cell hydridoma pr
MilliporeSigma™ Calbiochem™ PFKFB3 Inhibitor II, PFK15
A cell-permeable, bioavailable and more potent quinolinyl analog of PFKFB3 Inhibitor, 3PO (Cat
MilliporeSigma™ Calbiochem™ PKR/PERK Activator, DHBDC
A cell permeable dual activator of protein kinase R (PKR) and protein kinase R like kinase (PERK). Induces the phosphorylation of IκBα and thereby activates NF-κB pathway.
MilliporeSigma™ Calbiochem™ IRE1 Inhibitor IV, KIRA6
KIRA6, IRE1a Kinase Inhibitor.
MilliporeSigma™ Calbiochem™ ACE2 Inhibitor, MLN-4760
A cell-permeable, highly potent inhibitor of angiotensin converting enzyme 2 (ACE2; IC50 = 440 pM).
MilliporeSigma™ Calbiochem™ PKR Inhibitor, Negative Control
The PKR Inhibitor, Negative Control, also referenced under CAS 852547-30-9, controls the biological activity of PKR. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.
MilliporeSigma™ Calbiochem™ Piceatannol
A cell-permeable, substrate competitive and reversible plant metabolite that inhibits the activity of rat liver protein kinase A catalytic subunit (IC50 = 3μM), PKC (IC50 = 8μM), MLCK (IC50 = 12μM).
MilliporeSigma™ Calbiochem™ PRIMA-1
A cell-permeable quinuclidinone analog with antitumor properties.
MilliporeSigma™ Calbiochem™ Prodigiosin Serratia marcescens
A cell-permeable tripyrrole alkaloid compound that displays immunosuppressive and anti-tumor properties irrespective of p53 status and multidrug resistance.
MilliporeSigma™ Calbiochem™ Val-boroPro
An orally available amino boronic acid dipeptide with antihyperglycemic and anticancer properties
MilliporeSigma™ Calbiochem™ PI 3-Kα Inhibitor VIII
The PI 3-Kα Inhibitor VIII controls the biological activity of PI 3-Kα. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.
MilliporeSigma™ Calbiochem™ StemSelect™ Compound E
Notch signaling suppressor
MilliporeSigma™ Calbiochem™ STING Agonist, 2ʹ3ʹ-cGAMP
A cyclic-dinucleotide (cyclic-GMP-AMP) based compound that binds to the C-terminal domain of adaptor endoplasmic reticulum protein known as STING with high affinity (Kd = 4nM) and induces the synthesis of interferon-b (IFN-b) in mammalian cells (EC50 =
MilliporeSigma™ Calbiochem™ Proteasome Substrate III, Fluorogenic
Proteasome Substrate III, Fluorogenic, is a substrate for proteasome. Also acts as a substrate for calpain, chymotrypsin, and ingensin.